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KMID : 0360220110520050544
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Journal of the Korean Ophthalmological Society
2011 Volume.52 No. 5 p.544 ~ p.549
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The Change in Corneal Endothelial Cell Density after Pars Plana Vitrectomy
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Lee Ja-Young
Rhee Mi-Ri
Choi Kyung-Seek
Lee Sung-Jin
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Abstract
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Purpose: To assess the effect of pars plana vitrectomy and gas tamponade on corneal endothelial cell density.
Methods: The corneal endothelial cell density in 145 eyes that underwent pars plana vitrectomy was examined with a noncontact specular microscope 3 months pre- and post-operation. The subjects were divided as follows: Group 1 (32 eyes) underwent pars plana vitrectomy, group 2 (26 eyes) underwent pars plana vitrectomy combined with gas tamponade, group 3 (34 eyes) underwent pars plana vitrectomy combined with phacoemulsification and group 4 (48 eyes) underwent pars plana vitrectomy combined with phacoemulsification and gas tamponade. The changes in corneal endothelial cell density between groups was compared.
Results: The mean endothelial cell loss was more significant in group 2 than in group 1 (p = 0.012), and there was no difference between groups 3 and 4 (p = 0.063). However, after excluding 6 eyes that had blood in the center of the corneal endothelium as a result of being in the prone position following gas tamponade, the mean endothelial cell loss in group 2 was not less than in group 1. In eyes with blood in the corneal endothelium, endothelial cell loss significantly increased (p < 0.001).
Conclusions: The results of this study suggest that ophthalmic surgeons should attempt to carefully control bleeding and sufficiently irrigate the vitreous during pars plana vitrectomy combined with gas tamponade.
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KEYWORD
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Corneal endothelial cell loss, Gas tamponade, Phacoemulsification, Vitrectomy
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